Cerebral Palsy Research Today is a free monthly online journal that collates and summarizes the latest research about Cerebral Palsy, including details on symptoms, causes, types.

Cerebral palsy after maternal trauma in pregnancy.

Hayes B, Ryan S, Stephenson JB, King MD

Department of Neurology, Children's University Hospital, Dublin, Republic of Ireland.

Ten children (six males, four females) with spastic (n=9) and mixed spastic-dyskinetic (n=1) cerebral palsy were born at term to mothers who earlier in the pregnancy had been involved in accidents without suffering overt abdominal injury, placental abruption, or premature onset of labour. At follow-up (at ages 2-24y), Gross Motor Function Classification System levels were II (n=7) and V (n=3). Cognitive level was normal in five patients, while learning disability was mild to moderate in two and severe in three. Magnetic resonance imaging of the brain in all children, assessed blind to the dates of maternal trauma in pregnancy, showed lesions consistent with prenatal vascular insult at the time of the trauma. Feasible mechanisms of brain injury include reduced placental blood flow and/or placental embolization.

Published 27 August 2007 in Dev Med Child Neurol, 49(9): 700-6.
Full-text of this article is available online (may require subscription).

© 2004-2008 Cerebral Palsy Research Today. All Rights Reserved.